Use of Nanoparticles for Radiosensitization and Imaging
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PhysicsDescription
TiO2 nanoparticles are being developed to enhance the killing effects of ionizing radiation for use in cancer therapy. These nanoparticles can be detected in mammalian cells using synchrotron-based X-ray fluorescence microscopy. An Fe core permits detection by MR contrast and thus provides a means of detecting and treating cancer with a single nanoparticle. Targeting is achieved using surface receptors such as Epidermal Growth Factor.